Comments on: what effects does predisolone have on diabetes ?

By: cvicurn2005

cvicurn2005 — Thu, 22 Oct 2009 18:57:59 +0000

Steroid induced hyperglycemia (elevation of blood sugar while taking steroid) is what is happening to your father. Some chemo agents could also cause hyperglycemia, along with stress induced hyperglycemia(stress triggers the release of the flight or fight response hormones norepinephrine & epinephrine which leads to hyperglycemia). The treatment usually requires carb control, controlling the hyperglycemia with insulin while receiving steroids. Studies have shown that if you control blood sugars during hospitalization you could improve outcomes by decreasing wound infection and such. Hope this helps
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By: chanukyagv

chanukyagv — Thu, 22 Oct 2009 18:27:59 +0000

Steroid leads to increased glucose out put from liver and decreased uptake at muscle.Hence adding insulin and thiazolidinedione or metformin as condition permits ,will definitely control glucose levels,albeit at higher doses of insulin.
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S

By: ?? Peachy ??

?? Peachy ?? — Thu, 22 Oct 2009 17:54:59 +0000

My webpage has links to many natural health sites. If he follows my diet recommendations, he will not only lower his blood sugar, he will strengthen his immune system. There are lots of things you can do to improve his chances. First, is to get him on a healthy diet with plenty of antioxidants like blueberries, acai berries, goji berries and broccoli. Don’t believe everything the doctors tell you. Most medical doctors know very little about how to take care of a type 2 diabetic patient. You’ll have to trust me on this. Before you dismiss this as some sort of fanatic’s idea of a scam, go to my webpage and read the results of my most recent bloodwork…. I’m not making this stuff up.
http://www.geocities.com/seabulls69/Type_II_Diabetes.html
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The School of Hard Knocks.

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Even if it isn’t mine.

By: feliciter audax

feliciter audax — Thu, 22 Oct 2009 17:49:59 +0000

Prednisolone is a synthetic glucocorticoid which will raise blood sugar levels – how high, depends on the dose and whether the person already is diabetic. For diabetic patients, it is advisable to maintain the blood sugar levels between 5-7 mmol/L (90-126 mg/dl) for fasting and 7-12 mmol/L (126-200 mg/dl) post-meal, i.e.target HbA1c about 7-8%.

Since the prednisolone is necessary for chemo, your father may require increasing doses of oral hypoglycemic medication or insulin therapy to maintain healthy blood sugar levels. The doctors would be able to take care of that.
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I’m an endocrinologist

By: jimmysbeth

jimmysbeth — Thu, 22 Oct 2009 17:17:59 +0000

prednisone(a steroid) raises blood sugar,are they now giving him medication for his high blood sugar?
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I am a LPN

By: SAMI

SAMI — Thu, 22 Oct 2009 16:35:59 +0000

Prednisolone increases blood glucose. To get it to normal your father has to take recommended dose of insulin.
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By: Norton N

Norton N — Thu, 22 Oct 2009 16:17:59 +0000

When you say high this means different things to different people. Was it over 300?

As to prednisone, it tends to depress the immune system, and diabetes is an immune system disease. It will reduce the body’s ability to fight infection even while reducing inflamation.

Consult an Endocronologist.

Get Dad on the ADA exchange Diet, this will help his sugar levels.

I doubt the Doc would have ordered Prednisone for a Diabetic if the need had not been critical to great. If this is a short course, don’t worry. Long course steriods have detrimental effects, one of which is activating diabetes.

Not knowing the condition for which this Doc ordered this med, I can not really advise you.

I can tell you that long term steroid use can……cause diabetes…….bone problems………..sexual problems………emotional problems, and skin problems.

The negative effects of high sugars have to be balanced in the treatment. In other words, no reputable doc would prescribe steroids for your Father unless the need outweighed the risk.

Make Dad’s Doc discuss treatment with you, and don’t stop asking questions until you are satisfied. This is your job. Use internet search engines to acquaint yourself with the cancer your Father has, and treatments available. A good place to start is WebMD.com

Remember, a very high sugar can be controlled by doses of insulin. The inflamation this Doctor is treating probably is getting in the way of your Dad’s diabetes treatment. It is a question of prorities. You treat the most life threatening condition first. Particularly if its effects are controlable as with blood glucose.

Probably the inflamation (0r rejection) issue is more urgent, than your dad’s Blood Glucose Level.
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By: doc

doc — Thu, 22 Oct 2009 16:07:59 +0000

Yes,unfortunately.It is one of the side effects associated with Prednisolone.You may want to read this-
http://www.chemocare.com/bio/prednisolone.asp.
I am really sorry about your dad.
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By: suzyfirestarter

suzyfirestarter — Thu, 22 Oct 2009 15:47:59 +0000

Aka as Prednisone is a powerful steroid that has an anti inflammatory effect . Short term it is a great drug but long term can have adverse effects such as masking infection, raising blood sugar, increasing blood pressure,maldistribution of fat around the face and upper back among other adverse effects. The Prednisone will help your father breathe easier given the fact he has lung cancer. His blood sugar can be monitored closely and controlled with more effort.He may not necessarily get higher blood sugar levels. This does vary among individuals. I hope he is comfortable and enjoys what is left of his life with family, friends, and other loved ones.
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By: gamal_solimann

gamal_solimann — Thu, 22 Oct 2009 15:40:59 +0000

prednisilon is cortison..not recomended with diabetic patient..he should take..synacten,,it is corticotrophics not cortison
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